Black Woman's Skin Turns Lighter After Chemotherapy: Understanding the Medical Case

Tuesday, July 14, 2026

SAEDNEWS: Rare Cancer Treatment Causes Unexpected Skin Color Change in Middle-Aged Black Woman

Black Woman's Skin Turns Lighter After Chemotherapy: Understanding the Medical Case

According to Saednews, A 54-year-old Black woman, Paula Edwards, experienced a rare change in her skin color after taking medication prescribed for kidney cancer treatment.

Edwards was diagnosed with kidney cancer in 2012. At the time of her diagnosis, doctors believed her chances of survival were low. However, she has survived for several years and has undergone four major surgeries as part of her treatment.

Following her fourth operation, Edwards began taking Votrient (pazopanib), a medication used to treat advanced kidney cancer by slowing or stopping the growth of tumors. After starting the drug, she noticed that her skin gradually became lighter.

Initially, her doctors were unsure what caused the change. They later explained that, although extremely uncommon, Votrient can affect melanin—the pigment responsible for skin color—resulting in skin lightening in some patients.

In addition to this rare side effect, Votrient is more commonly associated with reactions such as skin rash, dry skin, itching, nausea, diarrhea, and an increased risk of blood clots.

The unexpected change in her appearance has created emotional and family challenges. Edwards has said that the transformation has affected her sense of identity, and she hopes the lightening of her skin will stop and not continue further.

Before her illness, Edwards worked as a security officer. Because of her changing appearance, some people wrongly assumed that she had undergone cosmetic procedures or skin-bleaching treatments to lighten her complexion. She has emphasized that the change was an unintended side effect of her cancer medication.

Despite these challenges, Edwards hopes to continue receiving the understanding and support of her family and friends as she focuses on her health and recovery.