Saed News: The link between irregular meal patterns and depression appears to be slightly stronger in men, smokers, and individuals who eat after 9 p.m.
According to SAEDNEWS, mental health specialists usually consider factors such as life events, genetics, and brain chemistry when treating mood disorders. However, in recent years researchers have increasingly focused on lifestyle factors, especially dietary patterns and meal timing.
A recent study suggests that eating regular meals at consistent times is associated with a lower likelihood of depressive symptoms. According to the study, individuals who frequently skip main meals report more symptoms of depression; however, having a diverse diet can somewhat weaken this association. The findings were published in the Journal of Affective Disorders.
Depression remains one of the leading causes of disability worldwide, affecting nearly 280 million people. While mental health treatment has traditionally focused on life events, genetics, and brain chemistry, researchers have recently paid more attention to lifestyle factors, particularly eating patterns and timing.
Meal timing can influence the body’s biological clock, or circadian rhythm, which regulates sleep, hormone secretion, and many bodily functions. Irregular eating may disrupt this natural cycle and disturb hormones such as cortisol, which plays an important role in stress response. As a result, a person’s ability to cope with psychological stress may decline.

Researchers also believe that irregular eating patterns can alter the composition of beneficial gut bacteria. Since there is a constant connection between the gut and the brain, disruption in this system may lead to mild but chronic inflammation in the body, a condition commonly observed in people with depression.
Most previous studies focused on food types, but research on meal timing was often limited to specific groups such as shift workers or adolescents. Therefore, Korean researchers decided to examine the issue on a larger scale.
In this study, Hyejin Tae and Jung-Ho Chae analyzed data from 21,568 adults participating in the Korea National Health and Nutrition Examination Survey between 2014 and 2022. Participants provided detailed information about their eating habits, health status, and lifestyle.
Researchers defined individuals with irregular eating patterns as those who consumed a main meal such as breakfast, lunch, or dinner fewer than five times per week. Dietary diversity was also assessed based on consumption of major food groups including grains, vegetables, fruits, meat, legumes and nuts, and dairy products.
Mental health status was evaluated using a standardized depression questionnaire that assesses symptoms such as hopelessness, low energy, and sleep disturbances.
Results showed that individuals with the most irregular eating patterns were 1.55 times more likely to experience depressive symptoms compared to those with regular meal schedules. In other words, the more irregular the eating pattern, the higher the likelihood of low mood.
Researchers also found that a diverse diet could reduce part of this negative effect. Individuals who consumed a wider variety of food groups were less affected by the psychological consequences of irregular eating. According to the researchers, a broad intake of vitamins and anti-inflammatory compounds, as well as maintaining a healthy gut microbiome, may help stabilize brain function.
In contrast, regularly skipping breakfast was associated with a higher risk of depression. According to researchers, skipping breakfast may disrupt metabolism and blood sugar regulation throughout the day and affect morning hormones that influence mood and cognitive performance.
The study found the worst mental health outcomes in individuals who both skipped breakfast and followed a low-diversity diet. Interestingly, even among those with highly diverse diets, skipping breakfast still had a significant negative effect.
Researchers also observed that the relationship between irregular meals and depression was slightly stronger in men, smokers, and those who ate after 9 p.m.
However, the researchers emphasized that this was a cross-sectional study, meaning it examined only a single time period. Therefore, it cannot be concluded with certainty that irregular eating causes depression. The relationship may also work in reverse—people with depression may skip meals due to reduced appetite or motivation.
Additionally, dietary data was self-reported, which may introduce recall bias. Information on sleep quality and stress levels was also not available, both of which can affect diet and mental health.
Despite these limitations, the researchers believe the findings suggest that “when you eat” may be as important as “what you eat” for mental health. They conclude that maintaining a regular eating schedule along with a varied diet may be a simple and accessible way to support mental well-being and reduce the risk of depression.