Saed News: Experts believe that one of the side effects of consuming foods containing artificial sweeteners is an increase in appetite and hunger.
According to SAEDNEWS, and the Community Nutrition Improvement Office of the Ministry of Health, Splenda as a sugar substitute may increase appetite and feelings of hunger in individuals, thereby increasing the likelihood of overeating. This finding is based on results published in the journal Nature Metabolism.
The main ingredient in Splenda, sucralose, appears to confuse the brain by providing a sweet taste without delivering the expected calories. According to researchers, “If your body expects calories due to a sweet taste but does not receive them, this can change how the brain responds to such foods over time and increase the desire to consume them.”
According to researchers, around 40% of Americans regularly use artificial sweeteners in an effort to reduce daily sugar intake, but do these substances really help control body weight?

Researchers, after examining the consumption of three types of beverages—plain water, a sucralose-sweetened drink, and a sugar-sweetened drink—showed that the sucralose drink, compared to water or sugar-containing drinks, increased activity in the hypothalamus region of the brain, which regulates appetite and body weight. In addition, sucralose consumption led to greater feelings of hunger compared to regular sugar-sweetened beverages. Interestingly, these effects were stronger in women and obese individuals, who are more likely to consume diet products.
Blood tests showed that consuming regular sugar increases blood glucose and triggers hormones such as insulin and GLP-1 (glucagon-like peptide-1), but sucralose does not have this effect. These hormones signal the brain that calories have been consumed and reduce the need for further food intake. Sucralose does not produce this satiety signal.
Children and adolescents are more vulnerable, as artificial sweetener consumption is more common among them and their brains are more sensitive at these ages. Therefore, this represents an important opportunity for early intervention.